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Fox, Edward |
Associate Professor, Behavioral Neuroscience Area
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703 Third Street
PSYC, room 3128 |
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West Lafayette |
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IN 47907 USA |
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Ph.D Purdue University, 1989
Why do we choose one behavior over another at any given moment? His interests are first to identify and characterize the neural systems involved in determining one's motivational state, and secondly to understand how this information interfaces with neural systems that control behavior.
For instance, he and others found that many eating disorders are driven by changes in the brain's control of metabolism that then change our appetite and cause us to eat too much or too little. He uses genetic engineering (mutant, transgenic and knockout mice) in combination with modern neuroscience techniques to understand how different neural and hormonal systems interact to control metabolism and appetite. Insights gained from these studies will provide a basis for understanding how neural systems are influenced by one's motivational state and provide new avenues for therapeutic intervention in disorders of eating and body weight.
Recent Publications:
Fox, E. A., & Murphy, M. C. (2008). Factors regulating vagal sensory development: potential role in obesities of developmental origin. Physiology and Behavior, 94, 90-104.
Murphy, M. C. & Fox, E. A. (2010). Mice deficient in brain-derived neurotrophic factor have altered development of vagal gastric sensory innervation. Journal of Comparative Neurology, 518(15), 2934-2951.
Fox, E. A. & McAdams, J. (2010). Smooth muscle-specific expression of neurotrophin-3 in the embryonic and neonatal gastrointestinal tract of the mouse. Cell and Tissue Research, 340(2), 267-286.
Biddinger, J. E. & Fox, E. A. (2010). Meal parameters and vagal gastrointestinal afferents in mice that experienced early postnatal overnutrition. Physiology and Behavior, 101, 184–191. |
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